Anti-Aging & Beauty
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Epithalon

Starting at
300
/month*

Epithalon is a longevity peptide shown to support cellular regeneration, promote healthy sleep cycles, and help reduce visible signs of aging from within.

  • Supports longevity and healthy aging
  • Enhances sleep quality and circadian rhythm
  • Boosts cellular repair and regeneration
  • Strengthens immune and hormonal balance
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Epithalon works by activating telomerase, an enzyme that helps rebuild and lengthen telomeres, the protective caps on DNA that naturally shorten with age. By supporting telomere integrity, it may slow cellular aging and enhance the body’s ability to repair and renew tissues. It also helps regulate melatonin production, improving circadian rhythm and restorative sleep.

Epithalon was first discovered in the 1980s by Dr. Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology during research on natural peptides derived from the pineal gland. Over several decades, animal and human studies have associated Epithalon with extended lifespan, improved immune function, and enhanced antioxidant defense. Clinical trials in Russia have shown potential benefits for age-related disorders, telomere length restoration, and overall well-being. Ongoing global research continues to explore its role in healthy aging and longevity optimization.

Epithalon is generally well-tolerated, with mild injection-site redness or temporary fatigue occasionally reported. No serious adverse effects have been observed in clinical studies when used under medical supervision.

See the Science

Epitalon peptide in telomerase-negative human fetal fibroblast culture induced expression of the catalytic subunit, enzymatic activity of telomerase, and telomere elongation2003

In cultured human fetal fibroblasts, Epithalon activated telomerase and elongated telomeres, highlighting its cellular-level anti-aging potential.
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Epitalon increases telomere length in human cell lines through telomerase up-regulation or ALT activity2025

In human epithelial and fibroblast cell lines, Epithalon treatment significantly extended telomere length via telomerase or ALT mechanisms, suggesting broad-spectrum cellular longevity effects.
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Epitalon protects against post-ovulatory aging-related damage of oocytes in vitro2021

In an in-vitro oocyte aging model, Epithalon reduced oxidative stress, improved mitochondrial membrane potential, and lowered spindle abnormalities indicating protective effects in cell-aging contexts.
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Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor development in mice2002

In a long-term study with mice, monthly injections of Epithalon increased maximum lifespan by ~12 % and reduced chromosomal aberrations, demonstrating geroprotective activity in a whole-organism model.
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AIRA encourages all patients to conduct their own research and consult with a qualified healthcare provider before beginning any peptide or prescription therapy. While we strive to provide accurate, science-based information, much of the existing research on compounds such as Epithalon is derived from preclinical or early-stage studies. These findings may not yet be fully validated in large-scale human trials. The content provided on this site is for informational and educational purposes only and should not be interpreted as medical advice or a guarantee of treatment efficacy. Individual results may vary based on health history, dosing, and other factors. Always discuss potential risks, benefits, and alternative options with your doctor or licensed medical provider prior to starting any new therapy.

Key Takeaways

Supports Healthy Aging

Early research suggests it may help keep cells working better as we get older.

Helps Protect Chromosomes

Lab studies show it may help maintain telomeres, or the “caps” that protect our DNA.

Cell Protection Benefits

Shown in preclinical research to help shield cells from stress and wear-and-tear.

Non-Hormonal Approach

Acts through natural peptide signaling rather than hormone alteration.

Frequently asked questions

Epithalon has not been approved by the U.S. Food and Drug Administration. It can only be prescribed through licensed clinicians where state law allows.

Yes, several small human studies, primarily in Eastern Europe and Russia, suggest potential benefits for aging biomarkers, immune support, and sleep quality.

Epithalon helps support healthy cell regeneration by activating telomerase, an enzyme that maintains the protective caps (telomeres) on DNA. This process may help slow cellular aging, support immune function, and promote balanced sleep cycles through pineal gland activity.

Available research suggests Epithalon is well tolerated with no serious side effects reported in human or animal studies. Mild injection-site redness or irritation can occur.

Anyone who is pregnant, nursing, or managing cancer or hormonal conditions should not use Epithalon unless specifically directed by a medical professional. Individuals with autoimmune disorders should discuss risks with their provider before starting therapy.

Epithalon is usually administered via subcutaneous injection, typically in the abdomen.

Epithalon is usually administered as a short course or cycle prior to a broader anti-aging or longevity protocol that may include TA-1 + LL-37, MOTS-C, NAD+, or CJC-1295 + Ipamorelin. Any stack should be clinician-supervised.

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Medical Intake

Complete a brief medical intake and receive a free consultation with a licensed provider.

Prescription

Expertly formulated for you and dispensed by one of our trusted U.S. pharmacy partners.

Delivery

Discreetly packaged and shipped straight to your door. Fast, secure, hassle-free.
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Why AIRA?

Your body already holds the blueprint — AIRA helps you unlock it. Our physician-guided peptide programs will help you perform, recover, and feel your best.

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